According to a study recently conducted by a cancer research laboratory in the Netherlands, the latest new vaccines for mesothelioma can prevent and treat mesothelioma, a form of cancer from exposure to asbestos. The researchers have tested the vaccine on 10 patients who had been diagnosed with mesothelioma, with all of them showed increased levels of antibodies to the disease and three of them showed that the tumor has decreased in size.
What symptoms of mesothelioma cancer?
The study, published in the American Journal of Respiratory and Critical Care Medicine, explained bagimana vaccines work by creating dendritic cells antigen on malignant mesothelioma of the lining fluid in the lungs of patients. Dr Joachim Aerts, the author of the study and lung specialist at the Erasmus Medical Center in Rotterdam, said that approach by using the patient's immune system to attack tumors useful and create immunity to the disease, compared with conventional radiation or chemotherapy treatments.
How mesothelioma histologic picture?
Dr. Aerts said that this is one form of a relatively new treatment for cancer called immunotherapy. Mesothelioma vaccine can be used and relatively safe, with few side effects when compared with current treatment methods. He expressed the hope that further study could improve the survival rates of patients with the disease mesotelioma. Currently, patients diagnosed with mesothelioma, the prognosis of his life just to live less than two years.
Patients who have been exposed to asbestos typically do not show symptoms of mesothelioma for several years or even decades, after the initial exposure period. At that time, metastase mesothelioma will continue to run in the lungs and seep into other organs. The other side of this study is that the vaccine could be a direct treatment for workers exposed to asbestos.
Although the side effects exhibited by patients in this study are not as bad as that experienced by patients undergoing chemotherapy or radiation treatments, one of the potential effect derived from the change from the patient's immune system during immunotherapy. The study noted that patients recovered quickly and showed no signs of autoimmune disease related.
Differences between pleural mesothelioma and peritoneal mesothelioma
Dr. Aerts noted the potential problems on immunosuppressive disorders. He said that the main problem for the treatment of mesothelioma is a tumor to create an environment in pleural mesothelium which can reduce the effects of the vaccine. He mentioned that the next step in vaccine development is how to provide immunosuppressive around to improve the effectiveness of cancer treatment.
Dr. Aerts and his fellow researchers have done some tests on the effects on dendritic cells and how they can affect cancer tumors in mice. Previous studies have shown that vaccination produces antibodies needed to destroy malignant cells and keep the surrounding healthy tissue to produce a specific immunity.
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